Revolutionizing cancer treatment: enhancing CAR-T cell therapy with CRISPR/Cas9 gene editing technology
CAR-T cell therapy, a novel immunotherapy, has made significant breakthroughs in clinical practice, particularly in treating B-cell-associated leukemia and lymphoma.However, it still faces challenges such as poor m&m speckled eggs persistence, limited proliferation capacity, high manufacturing costs, and suboptimal efficacy.CRISPR/Cas system, an ef